BNF August 2024 Update

This update contains 5 significant changes, 3 dose changes, and 3 new monographs.

Significant Changes:
•Immunisation schedule: updated guidance for immunisation against influenza.
•Influenza vaccine: updated guidance for immunisation.
•Medical emergencies in the community: updated guidance on the use of salbutamol in the management of acute asthma.
•Migraine: updated guidance to include atogepant for migraine prophylaxis.
•Topical corticosteroids: introduction of new labelling and a reminder of the possibility of severe side effects, including Topical Steroid Withdrawal Reactions [MHRA/CHM advice] (advice in relevant monographs; see example in betamethasone).

Dose Changes:
•Levomepromazine [update to palliative care indications and dosing].
•Midazolam [update to palliative care indications and dosing].
•Salbutamol [update to dosing for asthma; prophylaxis of allergen-or-exercise-induced bronchospasm; other conditions associated with reversible airways obstruction (adults only); and exacerbation of reversible airways obstruction (children only)].

New Monographs:
•Dzuveo® [sufentanil].
•Exblifep® [cefepime with enmetazobactam].
•Rystiggo® [rozanolixizumab].