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BNF November 2022 Update

This update contains 5 significant changes, 1 dose change, 4 new monographs and 6 new preparations.

Significant Changes:

  • COVID-19 vaccines: updated guidance for immunisation.
  • Methylphenidate hydrochloride long-acting (modified-release) preparations: caution if switching between products due to differences in formulations [MHRA/CHM advice].
  • Multiple sclerosis: updated guidance on management.
  • Nebulised asthma rescue therapy in children: home use of nebulisers in paediatric asthma should be initiated and managed only by specialists [MHRA/CHM advice] (advice in ipratropium bromide, salbutamol, terbutaline sulfate; see example in ipratropium bromide).
  • Rucaparib (Rubraca®): withdrawal of third-line treatment indication [MHRA/CHM advice].

Dose Changes:

  • Buprenorphine [update to indications and dose for transdermal patches].

New Monographs:

  • Sibnayal® [potassium citrate with potassium bicarbonate].
  • Tavneos® [avacopan].
  • Vydura® [rimegepant].
  • Vyepti® [eptinezumab].

New Preparations: Aloflute®, Avenor®, Seffalair Spiromax®, Sereflo Ciphaler®, Stalpex® [fluticasone with salmeterol]; Nuvaxovid® [COVID-19 vaccine].

For further details on changes in the BNF click on https://www.medicinescomplete.com/#/content/bnf/PHP107699