Martindale: The Complete Drug Reference September 2024 Update

This update contains 3 new monographs and 5 existing monographs have been updated. Preparations have also been updated for 4 countries.

New Monographs

• Mosunetuzumab is a bispecific recombinant monoclonal antibody that binds to both CD20 on B-cells and CD3 receptors on T-cells. It is used for the treatment of relapsed or refractory follicular lymphoma.
• Sparsentan is a dual endothelin and angiotensin II receptor antagonist. It is used to reduce proteinuria in primary immunoglobulin A nephropathy.
• Tofersen, an antisense oligonucleotide, is used for the treatment of amyotrophic lateral sclerosis associated with a superoxide dismutase 1 (SOD1) gene mutation.

Selective Updates – some new, re-validated or changed information

Monographs 

• Acetylcysteine
• Cytisinicline (formerly Cytisine)
• Macrogolglycerides (formerly Macrogol/glycerol Esters)
• Methylpyrrolidone (formerly N-Methylpyrrolidone)
• Trichloromonofluoromethane (formerly Trichlorofluoromethane)

Proprietary Preparations and Manufacturers updated for the following countries and regions:

• Australia
• Finland
• UK†
• USA†

† Countries updated on an ongoing basis