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BNF for Children November 2023 Update

This update contains 6 significant changes, 2 new monographs and 2 new preparations.

Significant Changes:

  • Methotrexate: advise patients to take precautions in the sun to avoid photosensitivity reactions [MHRA/CHM advice].
  • Quinolones: reminder of the risk of disabling and potentially long-lasting or irreversible side effects [MHRA/CHM advice] (see example in ciprofloxacin).
  • Quinolones: suicidal thoughts and behaviour [MHRA/CHM advice] (see example in ciprofloxacin).
  • Valproate: full pack dispensing [MHRA/CHM advice] (advice in sodium valproate, valproic acid; see example in sodium valproate).
  • Valproate: re-analysis of study on risks in children of men taking valproate [MHRA/CHM advice] (advice in sodium valproate, valproic acid; see example in sodium valproate).
  • Valproate: reminder of current Pregnancy Prevention Programme requirements; information on new safety measures to be introduced in the coming months [MHRA/CHM advice] (advice in sodium valproate, valproic acid; see example in sodium valproate).

New Monographs:

  • Skyrizi® [risankizumab].
  • Wegovy® [semaglutide].

New Preparations:

  • Demovo® [desmopressin]; Desmopressin sublingual tablets.