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British National Formulary June 2024 Update

This update contains 10 significant changes, 9 dose changes, 5 new monographs and 3 deleted monographs.

Significant Changes:

  • Antibacterials, use for prophylaxis: addition of antibacterial prophylaxis guidance for assisted vaginal birth (ventouse or forceps).
  • Borderline substances: products suitable for conditions requiring a ketogenic diet have been moved to a new section called Ketogenic diet.
  • Diabetic hyperglycaemic emergencies: updated guidance for management of individuals aged 16-18 years.
  • Immunisation schedule: updated guidance for herpes zoster (shingles) immunisation.
  • Meningococcal vaccines: updated guidance for immunisation.
  • Metformin hydrochloride: new indication and dose for type 1 diabetes mellitus.
  • Obstetrics: updated guidance for the prevention and treatment of haemorrhage.
  • Prescribing in renal impairment: update to CKD-EPI equation to remove race.
  • Sacubitril with valsartan: update to dose expression.
  • Varicella-zoster vaccines: updated guidance for immunisation against herpes zoster (shingles).

 

Dose Changes:

  • Bexsero® (meningococcal group B vaccine (rDNA, component, adsorbed)) [update to dosing].
  • Carbetocin [update to indication and dose].
  • Cyanocobalamin [update to dosing].
  • Ergometrine maleate [update to dosing for postpartum haemorrhage caused by uterine atony].
  • Ergometrine with oxytocin [update to dosing for active management of the third stage of labour].
  • Haemophilus influenzae type b with meningococcal group C vaccine [update to dosing].
  • Herpes-zoster vaccine (recombinant, adjuvanted) [update to dosing].
  • Meningococcal groups A with C and W135 and Y vaccine [update to dosing].
  • Oxytocin [update to dosing for active management of the third stage of labour].

 

New Monographs:

  • Adacel® [diphtheria with tetanus and pertussis vaccine].
  • Elrexfio® [elranatamab].
  • Omjjara® [momelotinib].
  • Opdualag® [nivolumab with relatlimab].
  • Velsipity® [etrasimod].

 

Deleted Monographs:

  • Artenimol with piperaquine phosphate.
  • Bambuterol hydrochloride.
  • Herpes-zoster vaccine (live).