9th December 2025

Psychotropic Drug Directory

This update contains changes to 23 records.

3.7 Old age has been revised and its name has been changed to 3.7 Older adults. A new record, 6.11
Weight gain, has been added to Management of side-effects, and
consequently 6.11 Others has been renamed 6.12 Others, side-effects.
Updates were also made to 1.4 Alcohol dependence and abuse, 1.13
Dementias, 1.14 Depression, and 1.15 Eating disorders to incorporate
literature on GLP-1 agonists; to 1.21 Psychosis and schizophrenia to add
literature on a new product recently licensed in the US; and to 3.9
Perinatal to include the latest MHRA drug safety information. Chapter 7
has also been updated with discontinued and relaunched products.
New: 6.11 Weight gain
Revisions: 3.7 Older adults
Minor updates: 1.4 Alcohol dependence and abuse; 1.13 Dementias;
1.14 Depression; 1.15 Eating disorders; 1.16 Insomnia; 1.21 Psychosis and
schizophrenia; 2.1.1 Hypnotics – relative side-effects; 2.1.2
Antidepressants – relative side-effects; 2.1.3 Antidepressants –
pharmacokinetics and receptor effects; 2.1.4 Antipsychotics – relative side-
effects; 2.1.5 Antipsychotics – pharmacokinetics and receptor effects;
2.1.6 Anxiolytics – relative side-effects; 3.2 Cardiovascular (CV) disease;
3.8 Parkinson’s disease (PD); 3.9 Perinatal; 3.10 Renal impairment; 4.1.1
Benzodiazepines; 6.5 Dermatological effects, 6.6 Endocrine effects; 6.12
Others, side-effects; 7.0 Psychotropic drugs.

9th December 2025

Stockley’s Interactions Checker

For December, 340 new interactions have been added, and 347 existing interactions have been updated.

9th December 2025

Clarke’s Analysis of Drugs and Poisons

• 1 fully revised chapter.
• Nitrous Oxide and ADB-BUTINACA as new monographs.
• Revisions to the Cocaine and Benzoylecgonine monographs.
• 4 minor updates.

9th December 2025

Martindale’s ADR Checker

This update contains 9 new drugs, 31 minor updates, and 162 new or updated pieces of short management advice. In addition, 16 existing drugs have been revalidated.

9th December 2025

Extended Stability for Parenteral Drugs

This update contains 5 new monographs and 5 revised monographs.

New monographs: Carfilzomib; Ceftobiprole medocaril sodium; Eculizumab; Nivolumab; Rezafungin.

Revised monographs: Ampicillin; Infliximab; Ketamine; Rituximab; Tigecycline.

9th December 2025

Palliative Care Formulary

This update contains 2 revised monographs.

The following monographs have been fully revised: Inhaled corticosteroids, Inhaled long-acting beta₂ agonists (LABAs).

The following monographs have been partially
updated: Bronchodilators, Ipratropium bromide, Salbutamol, Theophylline, Tiotropium.