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Prescribing Medicines for Children From drug development to practical administration

Prescribing Medicines for Children From drug development to practical administration

Edited by Mark Turner, Mike Sharland and Charlotte Baker



Your guide to delivering safe and effective medicines for children.

Published1st Jul, 2019
Dimensions234 x 156 mm
Page count619


Prescribing Medicines for Children covers a broad range of important topics in paediatric therapeutics, ranging from the principles of clinical pharmacology in children through to medication safety and drug development.   It is an international title that provides guidance on the principles behind optimal neonatal and paediatric prescribing globally.

Part I provides concise educational material relating to paediatric clinical pharmacology and optimising how medicines are developed and prescribed for children. It covers research methods for investigating paediatric medicines, from clinical trials through to pharmacoepidemiology and medicinal formulations.

Part II considers key clinical prescribing areas. Each chapter is focused on the key issues in prescribing for a respective clinical specialty or context, with a broad range of subjects from core topics of General Paediatrics through to Paediatric Intensive Care.

This book complements British National Formulary for Children (BNFC).

It is an indispensable reference guide for anyone involved in prescribing medicines to neonates and children. This includes students, nurses, paediatricians and primary care physicians and academic scientists.



  • General principles of paediatric clinical pharmacology
  • Pharmacokinetics
  • Drug absorption
  • Drug distribution: from birth to adolescence
  • Drug metabolism
  • Drug elimination
  • Pharmacodynamics: practical examples
  • Pharmacogenetics and pharmacogenomics
  • Modelling and simulation: pharmacometrics
  • Adverse drug reactions
  • Drug interactions
  • Pregnancy and lactation
  • Paediatric clinical pharmacology
  • Education: training programmes and competencies
  • The paediatric drug discovery pipeline
  • Understanding phase I clinical trials
  • Early phase clinical trials: adaptive designs
  • Phase IV studies and pharmacovigilance
  • Non-interventional studies
  • Pharmacoepidemiology
  • Innovative strategies in paediatric drug development
  • The role of the pharmaceutical industry in developing medicines for children
  • Paediatric drug formulations
  • Extemporaneous preparations of medicines for children
  • Excipients in medicines for children
  • The role of parents and children in paediatric medicines
  • The ethics of medicines research in children
  • Evidence-based prescribing
  • Improving training in prescribing
  • Electronic prescribing
  • Avoiding medication errors
  • Intravenous medicines administration
  • Team working in medicines administration
  • Evidence-based formularies
  • Therapeutic drug monitoring
  • Medicines for children in low to middle income countries
  • Optimal prescribing in the resource-poor setting


  • Gastrointestinal system
  • Cardiovascular system
  • Respiratory system
  • Antiepileptic drug therapy 305
  • Prescribing in infection: anti bacterials
  • Prescribing in infection: antifungals and antivirals 3
  • Endocrinology
  • Diabetes mellitus
  • Adolescent medicine
  • Nephrology
  • Prescribing blood and blood components
  • Oncology: cytotoxic drugs
  • Immunosuppressive agents in paediatric solid organ transplantation
  • Nutrition and metabolism
  • Rheumatology
  • Ophthalmology
  • Ear, nose and throat disorders
  • Medical therapy in dermatology
  • Immunological products
  • Prescribing vaccines: an overview
  • Sedation and anaesthesia
  • Palliative care
  • Pain management
  • Drugs and pharmacology in paediatric intensive care


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